The Argentine and Portuguese battled it out in La Liga for the better part of a decade after Ronaldo joined Real Madrid in 2009.
Barcelona star Messi and Ronaldo were the dominant forces in Spain and world football for much of their time in the league together, creating a natural rivalry between the pair.
During Ronaldo’s time with the Blancos, he won La Liga twice and lifted the Champions League four times.
Meanwhile, Messi has won an incredible nine La Liga titles (six of which were earned while Ronaldo was at Madrid) and also lifted the Champions League on four occasions.
Ronaldo’s spell in Spain ended prior to the current season, as the 33-year-old completed a sensational transfer to Juventus.
And Messi has claimed that the pair’s time at the top of the game in Spain was positive for football and for fans all over.
“The rivalry with Cristiano was very healthy and good for the fans,” the 31-year-old told Marca.
In the individual award department, Messi and Ronaldo have each won the Ballon d’Or five times, creating a duopoly on the award between 2008 and 2017.
That run was broken in 2018, with Ronaldo’s former Real Madrid team-mate Luka Modric lifting the prize and Messi controversially finishing fifth in the voting.
Messi finished behind Kylian Mbappe, Antoine Griezmann, Ronaldo and Modric, and has stated that he knew he would not win when he saw his competition for the award.
“I heard the nominees for the Ballon d’Or and I knew I wasn’t in the fight,” Messi said.
Despite all the success that Messi has had on the football pitch, he has insisted that there is still one higher priority in his life.
“I love football, but family is above all,” the Argentine stated.
Thank GOD someone finally said it. The most truth you will hear about the GOAT debate. I have been telling people this for a long time. It's about time someone had the balls to say it. #Ronaldo #WorldCup #WorldCupRussia2018 #messivsronaldo #LionelMessi pic.twitter.com/vljpUCdXsy
— Progressives Unite (@progressives8) June 21, 2018
Read what people on Twitter have to say about the rivalry.
https://twitter.com/theobondswell/status/1010347142672781312
This should settle this long standing rivalry : #MessivsRonaldo pic.twitter.com/09Q6sD6bn6
— KNOXPETE (@KNOXTAINMENT) August 24, 2018
Hmmmm, I think I'll take the one on the left. #MessiVSRonaldo pic.twitter.com/mPFGQtad5U
— Andrew Mathys (@AMathys0) July 10, 2016
Who u go bet for??? #MESSIvsRONALDO #ARGvsPOR pic.twitter.com/zR8nZm7mXz
— Katiboom (@kwawkese) November 18, 2014
Sorry guys it's official, Messi wins…. #WWE2K18 #MessivsRonaldo pic.twitter.com/27tEgf0dnC
— 𝘽𝙕𝙈 🎮 (@BigZombieMonkey) June 27, 2018
Pic Of The Day: Because Rivals, Not Enemies. #ElClasico #Madrid #Barcelona #Barca #Messi #Ronaldo #messivsronaldo #ronaldovsmessi pic.twitter.com/Aweg0lP1Pu
— Sir Jadeja fan (@SirJadeja) December 3, 2016